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Ninety-one-day repeated oral toxicity study in rats and dogs In addition to the GLP 91-d repeated oral toxicity study, described in this article, the oral toxicology of AEF0117 was studied in non-GLP (maximal tolerated dose and 14-d administration) and in a 28-d repeated administration (2, 9 and 36 mg d 1 ) GLP study in rats (Sprague Dawley SPF, 7 weeks old) and dogs (Beagle, 78 months old)

As such, the solicitations typically consist of topics relevant to the following organization focus areas: To learn more about the DHS SBIR Program and current solicitations please visit the SBIR program portal

The real goal in the long run is to preserve overall health. If approved in type 1 diabetes, adjunctive therapies could go a long way towards preventing heart and kidney damage and improving wellbeing in the long-term